Association of Venous Thromboembolism and Inflammatory Bowel Disease
| Autor: | Mitra Ahadi, Nikoo Saeedi, Mina Akbari Rad, Negin Masoudifar |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Cardio-Thoracic Medicine, Vol 11, Iss 2, Pp 1167-1176 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2345-2447 2322-5750 |
| DOI: | 10.22038/jctm.2022.65621.1381 |
| Popis: | Introduction: Studies have shown that patients with inflammatory bowel disease (IBD) have an increased risk for venous thromboembolism (VTE). VTEs causes significant morbidity and mortality.Methods: We carried out a comprehensive search through different online databases including PubMed, Google Scholar, Scopus, and Medline. We focused on some of patients-related factors that may affect the risk of VTE incidence among IBD patients and also reviewed current guidelines on the prophylactic regimen of the IBD patients.Results: Based on the previous studies, the hypercoagulable nature of the disease results from a complex interaction between the systems participating in the coagulation cascade, including endothelial cells, platelets, and coagulation factors. There are a number of clinical factors that increase the probability of VTE development which include disease activity, age, pregnancy, surgery, and medical treatment.Conclusion: Taken together, these data suggest to initiate prophylactic regimen in IBD patients and to adjust it regarding to the patient’s condition and the presence of other predisposing factors. |
| Databáze: | Directory of Open Access Journals |
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