Description of Leishmania (Leishmania) forattinii sp. n., a new parasite infecting opossums and rodents in Brazil

Autor: Elizaide L. A. Yoshida, Cesar A Cuba Cuba, Raquel da Silva Pacheco, Elisa Cupolillo, Celso Cruz Tavares, Gerzia M. C. Machado, Hooman Momen, Gabriel Grimaldi Junior
Jazyk: angličtina
Rok vydání: 1993
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 88, Iss 3, Pp 397-406 (1993)
Druh dokumentu: article
ISSN: 0074-0276
1678-8060
DOI: 10.1590/S0074-02761993000300008
Popis: A new parasite species of Leishmania is described, L. (Leishmania) forattinii sp. n., which was isolated from a pooled triturate of liver and spleen of a opossum (Didelphis marsupialis aurita) and from skin samples from a rodent (Proechmys iheringi denigratus), captured in primary forest on the Atlantic Cost of Brazil. Our results on the basis of biological and molecular criteria indicate that this taxonomically distinct parasite ias a new species of the L. mexicana complex, but closely related to L. (L.) aristidesi Laison & shaw, 1979, as revelated by phenetic and phylogenetic numerical analyses of the enzyme data. L. forattinii was clearly distinguishable from other Leishmania species of the genus usisng enzyme electrophoresis, monoclonal antibodies, molecular karyotypes, analysis of restriction enzyme digestion patterns of kinetoplast DNA (kDNA), as well as the use of kDNA hybridization procedures.
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