| Autor: |
Alberto Corona, Vincenzo De Santis, Domenico Vitale, Cecilia Nencini, Antonella Potalivo, Anna Prete, Nicoletta Barzaghi, Sara Tardivo, Marina Terzitta, Anna Malfatto, Luigi Tritapepe, Alessandro Locatelli, Mervyn Singer |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Canadian Journal of Respiratory Therapy, Vol 58 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2368-6820 |
| DOI: |
10.29390/cjrt-2022-018 |
| Popis: |
Background We report the characteristics, timing, and factors related to the decision to perform a tracheostomy in patients with confirmed COVID-19 infection admitted to eight Italian intensive care units (ICUs). Materials and methods Prospective observational cohort study of patients with COVID-19 disease on mechanical ventilation. Long-term functional impairment (up to 180 days' post-hospital discharge) was assessed using the Karnofsky scale. Kaplan--Meier analysis assessed differences in survival and freedom from tracheostomy in relation to ICU stay. Cox regression model was used to assess which variables impacted on tracheostomy as a categorical outcome. Results A total of 248 patients were recruited in the eight participating ICUs. Patients undergoing tracheostomy (n = 128) had longer ICU (25 (18--36) vs. 10 (7--16), P = 0.001) and hospital (37 (26.5--50) vs. 19 (8.5--34.5) P = 0.02) stays. ICU and hospital mortality of patients tracheostomized was 34% and 37%, respectively. Cumulative survival Kaplan--Meier analysis documented improved survival rates in patients undergoing tracheostomy (Log-Rank, Mantel--Cox = 4.8, P = 0.028). Median Karnofsky scale values improved over time but were similar between survivors receiving or not receiving tracheostomy. No healthcare worker involved in the tracheostomy procedure developed COVID-19 infection during the study period. Conclusions Patients with COVID-19 infection who underwent tracheostomy had a better cumulative survival but similar long-term functional outcomes at 30, 60, and 180 days after hospital discharge. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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