The role of neutrophilic extracellular traps in oncogenesis

Autor: Mereke Maratkyzy, Aruna Kosybaeva, Naylya Kabildina, Anelya Beisenaeva
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Ķazaķstannyṇ Klinikalyķ Medicinasy, Vol 1, Iss 51, Pp 16-20 (2019)
Druh dokumentu: article
ISSN: 1812-2892
2313-1519
DOI: 10.23950/1812-2892-JCMK-00664
Popis: Views on the role of extracellular neutrophilic traps in oncology vary greatly. On the one hand, there is evidence of the anticarcinogenic properties of neutrophil networks associated with the direct destruction of tumor cells and stimulation of the immune system. Cytotoxicity towards tumor cells is manifested by trap components (myeloperoxidase, proteinases and histones), while DNA strands are considered as a kind of tool for capturing tumor cells and limiting their further spread.
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