Impact of Antithrombin Activity Levels Following Recombinant Antithrombin Gamma Therapy in Patients with Sepsis-Induced Disseminated Intravascular Coagulation

Autor: Tomohiko Akahoshi MD, PhD, Noriyuki Kaku MD, PhD, Yuji Shono MD, PhD, Yuzo Yamamoto MD, PhD, Keita Takahashi MD, PhD, Takeshi Iyonaga MD, PhD, Kenta Momii MD, Masaaki Nishihara MD, PhD, Jun Maki MD, PhD, Kentaro Tokuda MD, PhD, Ken Yamaura MD, PhD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Druh dokumentu: article
ISSN: 1938-2723
10760296
DOI: 10.1177/10760296221135790
Popis: Recombinant antithrombin gamma (rAT) is reported as an effective drug for patients with disseminated intravascular coagulation (DIC) in Japan. As the appropriate dose and targeted AT activity remain unknown, this study aimed to determine these aspects for sepsis-induced DIC. Thirty-one patients with septic shock and DIC with AT levels
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