Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
| Autor: | Sunil U. Tekale, Sushma S. Kauthale, Kavita M. Jadhav, Rajendra P. Pawar |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Journal of Chemistry, Vol 2013 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2090-9063 2090-9071 |
| DOI: | 10.1155/2013/840954 |
| Popis: | An efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the reaction medium, it serves as a green route for the synthesis of pyrano[2,3-c]pyrazoles. The advantages associated with the present protocol include nonchromatographic purification technique, use of recyclable heterogeneous nano-ZnO catalyst in aqueous medium, and short reaction time. It combines successfully the synergistic effect of green chemistry with nanocatalysis. |
| Databáze: | Directory of Open Access Journals |
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