Postpartum Hemorrhage in Heterozygote Factor XIII Deficient Women Compared With Healthy Women. A Cross-Sectional Experience From Iran

Autor: Majid Naderi, Ilia Mirzaei, Saeedeh Yaghoubi, Ida Milani, Nader Cohan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Druh dokumentu: article
ISSN: 1938-2723
10760296
DOI: 10.1177/10760296211051714
Popis: Postpartum hemorrhage (PPH) is a major cause of maternal mortality, which is a common clinical manifestation in women with rare bleeding disorders. In this study, we compare PPH and its complications in heterozygote factor XIII (FXIII) deficient women with healthy women. In this cross sectional case study, 50 women with heterozygote FXIII deficiency and 50 healthy women are evaluated. Data were initially collected by interviewing the women who were receiving FXIII replacement therapy after their childbirths. Data were analysed using SPSS (Version 22) and a P -value of less than .05 was considered statistically significant. The mean age in the patient and control groups were 31.2 and 32.5 years respectively. The occurring rate of PPH in the patient group was significantly higher than the control group (34% vs 2%) ( P -value
Databáze: Directory of Open Access Journals