A Rare Cause of Drug-Induced Skin Rash and Eosinophilia

Autor: Harun Muglu, Erdem Sunger, Celalettin Herek, Ozcan Sonmez, Fatih Pektas, Erdal Gundogan, Hakan Sari, Ahmet Engin Atay, Numan Gorgulu
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Bagcilar Medical Bulletin, Vol 3, Iss 1, Pp 11-13 (2018)
Druh dokumentu: article
ISSN: 2547-9431
DOI: 10.5350/BMB20180115061130
Popis: Allopurinol is a well-known drug to treat hyperuricemia in patients with chronic kidney disease, gout, or tumor lysis syndrome. The most common side effects are nausea, vomiting, elevated liver enzyme, pancreatitis, and skin rashes. Drug reaction with eosinophilic and systemic symptoms (DRESS) syndrome is a rare but life-threating complication of allopurinol treatment. Here, we present a 60-year-old male patient admitted with skin rashes, stomatitis, dyspnea, jaundice, elevated liver enzymes, acute renal failure, and eosinophilia, who was diagnosed with allopurinol-related DRESS syndrome.
Databáze: Directory of Open Access Journals