Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P
| Autor: | Jiaqiang Zhu, Wei Huang, Jing Zhao, Loc Huynh, Derek J. Taylor, Michael E. Harris |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 07037546 |
| DOI: | 10.1038/s41467-022-32843-7 |
| Popis: | Ribonuclease P efficiently processes all tRNA precursors despite sequence variation at the site of cleavage. Here, authors use high-throughput enzymology and cryoEM to reveal conformational changes that drive recognition by bacterial RNase P. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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