The Effectiveness of Lactobacillus plantarum Administration in Patients with Atopic Dermatitis
| Autor: | Ismatu Aghni Fatwa Izzati, Ratih Pramuningtyas, Rochmadina Suci Bestari, Nurhayani Nurhayani |
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| Jazyk: | English<br />Indonesian |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Magna Medika, Vol 9, Iss 1, Pp 43-50 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2407-0505 2774-2318 |
| DOI: | 10.26714/magnamed.9.1.2022.43-50 |
| Popis: | Background: Atopic dermatitis is a chronic and residual inflammatory skin disease with increased prevalence in every year. The medications that are often given can cause serious side effects if it given in the long-term. The treatment of Lactobacillus plantarum is expected to be safer long-term treatment option for patient with atopic dermatitis. Objective: The objective is to determine the effectiveness treatment of Lactobacillus plantarum in patients with atopic dermatitis. Method: The research design was a Systematic Review with a qualitative approach using meta-synthesis analysis type. The search was conducted on 3 databases: PubMed, Science Direct, and Google Scholar. Result: Total articles obtained were 239 with 16 duplicate data. 211 articles were included in the exclusion criteria and 5 articles were interventions with combination probiotics. So there are 7 articles included in the research with clinical trials, open trials, pilot studies, and 4 research using the randomized controlled trial Double Blind design. All results showed improvement in symptoms with the SCORAD index or Skindex-16. Several studies also measured IgE, IL-4, IL-10, IL-13, IL-17, the percentage of Th1, Th2, Treg, TGF-β, IFN-γ and obtained different results. Conclusion: Treatment of Lactobacillus plantarum in patients with atopic dermatitis is effective to reducing symptoms and as an immunomodulator. |
| Databáze: | Directory of Open Access Journals |
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