| Autor: |
Raquel Chamorro-Garcia, Carlos Diaz-Castillo, Bassem M. Shoucri, Heidi Käch, Ron Leavitt, Toshi Shioda, Bruce Blumberg |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-01944-z |
| Popis: |
Early life exposure to endocrine disrupting chemicals has been linked to increased adiposity during adulthood. Here Chamorro-García et al. show that ancestral exposure to the obesogen tributyltin causes obesity in untreated F4 generation male descendants by inducing heritable changes in genome architecture that promote a thrifty phenotype. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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