Association of antioxidant status and inflammatory markers with metabolic syndrome in Thais

Autor: Kanjana Suriyaprom, Sarunya Kaewprasert, Pumpath Putpadungwipon, Pisit Namjuntra, Suwit Klongthalay
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Health, Population and Nutrition, Vol 38, Iss 1, Pp 1-7 (2019)
Druh dokumentu: article
ISSN: 2072-1315
DOI: 10.1186/s41043-018-0158-9
Popis: Abstract Background An oxidant/antioxidant disequilibrium has been suggested as having a role in the pathogenesis of some diseases. Metabolic syndrome (MS) is significantly associated with cardiovascular disease and type 2 diabetes. The pathogenesis of MS is complex and not well understood. The purposes of the present study were to compare enzymatic and non-enzyme antioxidants, anthropometric, hematological, and biochemical findings between subjects with MS and without MS and to evaluate the relationship between antioxidant status and hematological parameters with the components of MS. Methods Metabolic syndrome was assessed by using the modified National Cholesterol Education Program, Adult Treatment Panel III criteria. Three hundred Thais, 124 with MS and 176 without MS, were included in the study. Each subject was tested for erythrocyte superoxide dismutase (SOD), glutathione peroxidase, (GPX), catalase (CAT), albumin and vitamin C levels, and hematological findings. Results Subjects with MS had lower SOD and CAT levels than those without MS (p
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