A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes

Autor:	Mohammad Rafiee, Mohammad Abbasi, Hassan Rafieemehr, Amin Mirzaeian, Mohieddin Barzegar, Vahid Amiri, Shaghayegh Shahsavan, Mohammad Hossein Mohammadi
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	engraftment graft vs host disease hematopoietic stem cell transplantation outcomes relapse survival Medicine
Zdroj:	Health Science Reports, Vol 4, Iss 2, Pp n/a-n/a (2021)
Druh dokumentu:	article
ISSN:	2398-8835
DOI:	10.1002/hsr2.282
Popis:	Abstract Background and aims As a curative procedure, hematopoietic stemcell transplantation (HSCT) is an approved treatment for many malignant orbenign hematologic and non‐hematologic diseases. There are different outcomes of HSCT, as well as several parameters influencing these outcomes. Methods We had searched scientific sources like Web ofScience and PubMed with a combination of keywords such as HSCT, engraftment,survival, outcomes, etc. Totally, 80 articles were included. Results Here we have reviewed the effective factors onmain outcomes of HSCT including engraftment, survival, graft versus hostdisease, and Mobilization. Also, the prediction of hematological reconstitutionand some novel suggestions leading to better outcomes are reviewed. Conclusion The study will be applicable for improvedmanagement of autologous and allogeneic HSCT process to increase the procedureefficiency.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ce6a30c23176471c91988347989c98b7 Zobrazit plný text záznamu Plný text View record in DOAJ