Free radical destruction of hydroxyl-containing amino acids
Autor: | Anastasia A. Sladkova, Irina P. Edimecheva, Anna A. Sosnovskaya, Oleg I. Shadyro |
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Jazyk: | Belarusian<br />English<br />Russian |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Журнал Белорусского государственного университета: Химия, Iss 1, Pp 3-13 (2019) |
Druh dokumentu: | article |
ISSN: | 2520-257X 2617-3980 |
DOI: | 10.33581/2520-257X-2019-1-3-13 |
Popis: | А new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established. It has been shown that substances with reducing properties are inhibitors of this process, while oxygen does not affect the probability of its occurrence. The data obtained are relevant for the development of novel approaches to the search for effective free radical processes regulators. |
Databáze: | Directory of Open Access Journals |
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