Free radical destruction of hydroxyl-containing amino acids

Autor: Anastasia A. Sladkova, Irina P. Edimecheva, Anna A. Sosnovskaya, Oleg I. Shadyro
Jazyk: Belarusian<br />English<br />Russian
Rok vydání: 2019
Předmět:
Zdroj: Журнал Белорусского государственного университета: Химия, Iss 1, Pp 3-13 (2019)
Druh dokumentu: article
ISSN: 2520-257X
2617-3980
DOI: 10.33581/2520-257X-2019-1-3-13
Popis: А new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established. It has been shown that substances with reducing properties are inhibitors of this process, while oxygen does not affect the probability of its occurrence. The data obtained are relevant for the development of novel approaches to the search for effective free radical processes regulators.
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