Aberrant Interhemispheric Connectivity in Obstructive Sleep Apnea–Hypopnea Syndrome

Autor: Yu-Ting Liu, Hui-Xin Zhang, Hui-Jun Li, Ting Chen, Ya-Qing Huang, Lian Zhang, Zhi-Chun Huang, Bin Liu, Ming Yang
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Frontiers in Neurology, Vol 9 (2018)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2018.00314
Popis: ObjectiveTo determine the changes in interhemispheric functional coordination in patients with obstructive sleep apnea–hypopnea syndrome (OSAHS) relative to controls, using a recently introduced method of analysis: voxel-mirrored homotopic connectivity (VMHC).MethodsTwenty-nine patients with OSAHS and twenty-six normal sex-, age-, and education-matched controls were recruited and resting-state functional magnetic resonance imaging data were obtained. We employed VMHC to analyze the interhemispheric functional connectivity differences between groups. The z-values of alterations in VMHC in brain region were correlated with clinical characteristics.ResultsCompared with controls, patients with OSAHS had significantly higher scores for body mass index (t = 5.749, P
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