Stroke and cardiovascular risk factors among working-aged Finnish migraineurs

Autor: Marja-Liisa Sumelahti, Merika S. Sumanen, Kari J. Mattila, Lauri Sillanmäki, Markku Sumanen
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Public Health, Vol 21, Iss 1, Pp 1-7 (2021)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-021-11006-1
Popis: Abstract Background The aim of our study was to evaluate the risk for comorbid cardio- and cerebrovascular diseases in the working-aged migraine population of Finland. Methods A total of 1505 cases who reported diagnosed migraine and 3010 controls from a cohort of 11,596 cases in the Finnish Health and Social Support Study were included. The study material was linked with two registers. ICD diagnoses I63 for ischemic stroke (IS), I21 − I22 for acute myocardial infarction (AMI), and G43 for transient ischemic attack (TIA) among study participants were drawn from the national Finnish Care Register for Health Care at the follow-up in 2012. Reimbursed triptan prescriptions were drawn from the national Social Security Institution (SII) data. The self-reported vascular risk factors were hypertension, high cholesterol values, any diabetes, myocardial infarction, stroke, and TIA. Odds Ratios (OR) with 95% confidence (95% CI) intervals were assessed for diagnosed stroke, myocardial infarction, and TIA. Results Migraineurs were mostly female (82%) and ≥ 54 years old (62%). Triptans were reimbursed among 34.7% of migraineurs. A self-reported hypertension (21%), high serum cholesterol (38%), and any diabetes (7%) were more common among migraineurs vs controls (p
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