Time trend in transcatheter aortic valve implantation: an analysis of the Spanish TAVI registry

Autor: Pilar Jiménez-Quevedo, Antonio Muñoz-García, Ramiro Trillo-Nouche, Raquel del Valle, José María de la Torre Hernández, Luisa Salido, Enrique Gutiérrez, Manuel Pan, Joaquín Sánchez-Gila, Bruno García del Blanco, Raúl Moreno, Roberto Blanco Mata, Juan Francisco Oteo, Ignacio Amat-Santos, Ander Regueiro, Francisco Ten, Juan Manuel Nogales, Eduard Fernández-Nofrerias, Leire Andraka, María Cruz Ferrer, Eduardo Pinar, Rafael Romaguera, Carlos Cuellas Ramón, Fernando Alfonso, Sergio García-Blas, Antonio Piñero, Julia Ignasi, Rocío Díaz Méndez, Pascual Bordes, Juan Meseguer, Luis Nombela-Franco
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2020
Předmět:
Zdroj: REC: Interventional Cardiology (English Ed.), Vol 2, Iss 2, Pp 98-105 (2020)
Druh dokumentu: article
ISSN: 2604-7322
DOI: 10.24875/RECICE.M20000104
Popis: ABSTRACT Introduction and objectives: This study primary endpoint was to present the in-hospital all-cause mortality of the Spanish TAVI registry from its inception until 2018. Secondary endpoints included other in-hospital clinical events, 30-day all-cause mortality, and an assessment of the time trend of this registry. Methods: All consecutive patients included in the Spanish TAVI registry were analyzed. In this time-based analysis, the population was been divided into patients treated before 2014 (cohort A: 2009-2013) and patients treated between 2014 and 2018 (cohort B). Results: From August 2007 to June 2018, 7180 patients were included. The mean age was 81.2 ± 6.5 years and 53% were women. The logistic EuroSCORE was 12% (8-20). Transfemoral access was used in 89%. In-hospital and 30-day all-cause mortality was 4.7% and 5.7%, respectively. On the time-based analyses during the hospital stay, the rate of myocardial infarction, stroke, need for pacemakers, tamponade, coronary obstruction, and vascular complications was similar between both groups. However, cohort B showed less need for conversion to surgery and malapposition of the valve. Also, the implant success rate increased from 93% to 96% (P< .001). In-hospital and 30-day all-cause mortality was significantly lower in cohort B, ([OR, 0.65; IC95%, 0.48-0.86; P= .003] and [OR, 0.71; IC95%, 0.54-0.92; P= .002], respectively). Conclusions: The time trend analysis of the Spanish TAVI registry showed a change in the patients’ clinical profile and an improvement in the in-hospital clinical outcomes and 30-day all-cause mortality in patients treated more recently.
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