Serum D-dimer and IL-33 in patients with chronic urticaria

Autor: Chang-qing XIAO, Li-qian PENG, Hua-ping LI, Run-xiang LI, Zhen-jie LI, Hui-lan ZHU
Jazyk: čínština
Rok vydání: 2020
Předmět:
Zdroj: Pifu-xingbing zhenliaoxue zazhi, Vol 27, Iss 6, Pp 397-399,404 (2020)
Druh dokumentu: article
ISSN: 1674-8468
DOI: 10.3969/j.issn.1674-8468.2020.06.004
Popis: Objective: To explore the levels and clinical characteristics of serum D-dimer and IL-33 in patients with chronic urticaria. Methods: A total of 63 patients with chronic urticarial were divided into a positive group and a negative group according to the results of the autologous serum skin test, in addition, a normal control group was set. The levels of serum D-dimer and IL-33 were measured by ELISA in all three groups. Results: Of the 63 patients with chronic urticaria, 37 were positive for ASST, 26 were negative for ASST. Serum levels of D-dimer and IL-33 in patients with chronic urticaria of the positive group were significantly higher than that in normal controls (all P0.05). Conclusion: The levels of D-dimer are high in patients with chronic urticaria, the levels of IL-33 are high in positive group, and these elevated D-dimer and IL-33 may lead to the imbalance of the immune system and increase the occurrence and development of chronic urticaria.
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