Sterilized Anopheles funestus can autodisseminate sufficient pyriproxyfen to the breeding habitat under semi-field settings

Autor: Hamisi J. Kunambi, Halfan Ngowo, Ali Ali, Naomi Urio, Amos J. Ngonzi, Yohana A. Mwalugelo, Mohamed Jumanne, Augustino Mmbaga, Felista S. Tarimo, Joseph Swilla, Fredros Okumu, Dickson Lwetoijera
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Malaria Journal, Vol 22, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1475-2875
DOI: 10.1186/s12936-023-04699-9
Popis: Abstract Background Anopheles funestus, the main malaria vector, prefer to oviposit in permanent and/or semi-permanent breeding habitats located far from human dwellings. Difficulties in identifying and accessing these habitats jeopardize the feasibility of conventional larviciding. In this way, a semi-field study was conducted to assess the potential of autodissemination of pyriproxyfen (PPF) by An. funestus for its control. Methods The study was conducted inside a semi-field system (SFS). Therein, two identical separate chambers, the treatment chamber with a PPF-treated clay pot (0.25 g AI), and the control chamber with an untreated clay pot. In both chambers, one artificial breeding habitat made of a plastic basin with one litre of water was provided. Three hundred blood-fed female An. funestus aged 5–9 days were held inside untreated and treated clay pots for 30 min and 48 h before being released for oviposition. The impact of PPF on adult emergence, fecundity, and fertility through autodissemination and sterilization effects were assessed by comparing the treatment with its appropriate control group. Results Mean (95% CI) percentage of adult emergence was 15.5% (14.9–16.1%) and 70.3% (69–71%) in the PPF and control chamber for females exposed for 30 min (p
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