Herlyn Werner Wunderlich Syndrome Presenting with Ischemic Stroke due to Suspected Paroxysmal Nocturnal Hemoglobinuria: A Case Report

Autor: Ayushma Acharya, Prajwala Yogi, Pramod Singh, Tulsi Ram Bhattarai
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Nepal Medical Association, Vol 59, Iss 234 (2021)
Druh dokumentu: article
ISSN: 0028-2715
1815-672X
DOI: 10.31729/jnma.5838
Popis: Paroxysmal nocturnal hemoglobinuria can rarely present as cerebral ischemia and stroke due to arterial thrombosis. However, it should be considered in a young patient with bone marrow failure features, systemic thromboses, and hemolysis. The variants of paroxysmal nocturnal hemoglobinuria pose a diagnostic challenge and hence are important to recognize. We report a case of a 28-years-old female with Herlyn Werner Wunderlich Syndrome who presented with an ischemic cerebrovascular accident, pancytopenia, hemoglobinuria, and widespread abdominal thromboses suggestive of paroxysmal nocturnal hemoglobinuria. The patient was managed symptomatically and referred toa hematologist.
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