| Autor: |
Roy Matkovic, Marina Morel, Sophie Lanciano, Pauline Larrous, Benjamin Martin, Fabienne Bejjani, Virginie Vauthier, Maike M. K. Hansen, Stéphane Emiliani, Gael Cristofari, Sarah Gallois-Montbrun, Florence Margottin-Goguet |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-27650-5 |
| Popis: |
The human silencing hub (HUSH) complex, which includes TASOR, deposits repressive marks on HIV proviruses, resulting in gene repression. Here, Matkovic et al. show that TASOR interacts with RNA Polymerase II, predominantly under its elongating state, and RNA degradation proteins to repress HIV provirus expression. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full text from SpringerLink