Adolescent Diet Quality and Cardiovascular Disease Risk Factors and Incident Cardiovascular Disease in Middle‐Aged Women

Autor: Christina C. Dahm, Andrea K. Chomistek, Marianne Uhre Jakobsen, Kenneth J. Mukamal, A. Heather Eliassen, Howard D. Sesso, Kim Overvad, Walter C. Willett, Eric B. Rimm, Stephanie E. Chiuve
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 12 (2016)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.116.003583
Popis: BackgroundPrimary prevention of cardiovascular disease (CVD) focuses on treatment of risk factors, including hypercholesterolemia, hypertension, and type 2 diabetes mellitus. We investigated whether a healthy diet in adolescence prevents development of clinical risk factors or incidence of CVD in adulthood. Methods and ResultsWe examined the time to the first development of ≥1 clinical risk factor (hypercholesterolemia, hypertension, or type 2 diabetes mellitus) or CVD in relation to a high school Alternative Healthy Eating Index (HS‐AHEI) within the Nurses’ Health Study II. Among those who completed a food frequency questionnaire about their high school diet and adult diet (mean age 42 years), 27 406 women free of clinical risk factors and 42 112 women free of CVD in 1998 were followed to June 2011. Hazard ratios (HRs) and 95% CIs were adjusted for potential confounders in high school and adulthood. We documented 11 542 first diagnoses of clinical risk factors and 423 CVD events. The HS‐AHEI was associated with a lower rate of risk factors (HR highest versus lowest quintiles 0.82; 95% CI, 0.77–0.87 [P trend
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