| Autor: |
Joseph Wang’ang’a Oundo, Shewit Kalayou, Gerrit Gort, Gebbiena M. Bron, Constantianus J.M. Koenraadt, Quirine ten Bosch, Daniel Masiga |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Parasite Epidemiology and Control, Vol 27, Iss , Pp e00384- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6731 |
| DOI: |
10.1016/j.parepi.2024.e00384 |
| Popis: |
The entomopathogenic fungus Metarhizium anisopliae isolate ICIPE 7 is being developed as an eco-friendly alternative to chemical acaricides in managing natural tick infestation on livestock. Its impact on tick infestation and tick-borne infections in cattle under natural conditions are yet unclear. We conducted a randomized controlled field trial to assess the safety and effects of Tickoff® (a formulation of M. anisopliae isolate ICIPE 7) and the chemical acaricide Triatix® on tick infestation and incidence of Anaplasma marginale and Theileria parva in extensively grazed zebu cattle in coastal Kenya. A total of 217 eligible herds comprising 1459 intent-to-treat zebu cattle were enrolled from 12 villages. The herds were randomly assigned in a 1:1:1 ratio to Tickoff®, Triatix®, or Tickoff® excipients. Tick counts, treatment administrations, and adverse events were registered every two weeks for seven months. The mortality of ticks collected from treated cattle was monitored in vitro. Infections with A. marginale and T. parva were monitored every two months. No adverse events were reported in either treatment group. Tickoff® did not significantly affect tick infestation (p = 0.869) or infection incidence (p > 0.05) compared to excipients. Triatix® significantly reduced tick infestation (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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