Traditional cardiovascular risk factors and atherosclerosis in patients with systemic sclerosis

Autor: S. S. Shabanova, L. P. Ananjeva, T. V. Popkova, E. S. Mach, D. S. Novikova, M. N. Starovoytova, L. N. Kashnikova, E. L. Nasonov
Jazyk: ruština
Rok vydání: 2016
Předmět:
Zdroj: Научно-практическая ревматология, Vol 45, Iss 4, Pp 24-30 (2016)
Druh dokumentu: article
ISSN: 1995-4484
1995-4492
DOI: 10.14412/1995-4484-2007-24-30
Popis: Objective. To assess frequency of traditional cardiovascular risk factors, clinical and subclinical atherosclerosis features in patients with systemic sclerosis (SS).Material and methods. 70 pts with definite diagnosis of SS ( 66 female and 4 male with mean age 46±10,8 years) were included. Control group consisted of 50 relatively healthy volunteers without systemic rheumatic diseases and Raynaud’s phenomenon, matched on sex and age. Classic risk factors of atherosclerosis were analyzed. Total coronary risk (TCR) (10-years risk of cardiovascular catastrophes development) was assessed with Framingham scale. Carotid sonographic examination with intima-media complex thickness (IMT) measurement using a 7.5 MHz frequency linear transducer was performed in 60 SS pts and 45 volunteers with Voluson 730 Expert apparatus (Austria).Results. Frequency of traditional cardiovascular risk factors and TCR was comparable in in SS pts and control. Menopause was more frequent in SS pts (p=0,005). Coronary heart disease was more frequent SS pts (13% versus 2%, p
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