NEUROCOGNITIVE SCREENING IN ISCHEMIC HEART DISEASE PATIENTS WHO NEED SURGICAL TREATMENT

Autor: M. A. Litvinenko, A. S. Kotov, S. V. Romanov, S. A. Terpigorev, T. G. Kabanova, M. N. Borisova
Jazyk: ruština
Rok vydání: 2016
Předmět:
Zdroj: Alʹmanah Kliničeskoj Mediciny, Vol 0, Iss 39, Pp 51-55 (2016)
Druh dokumentu: article
ISSN: 2072-0505
2587-9294
DOI: 10.18786/2072-0505-2015-39-51-55
Popis: Background: Coronary artery atherosclerosis is one of the main causes of ischemic heart disease. Formation of chronic vascular brain insufficiency in ischemic heart disease has a complex pathogenesis and can be related to a lower cardiac output. Occurrence and progression of neurodegenerative process in such patients can manifest by significant cognitive impairment deteriorating their quality of life and leading to social disadaptation.Aim: To assess neuropsychological functions in patients with coronary artery atherosclerosis and to identify potential risk factors predisposing to the development of cognitive and neurological impairment.Materials and methods: The study included 30 patients with stable angina requiring coronary surgical interventions and 25 patients with acute coronary syndrome. The patient age was 57.3 ± 1.8 and 58.3 ± 10.9 years, respectively. In 15 of cases, acute coronary syndrome was associated with ST elevation on ECG and in 10 of cases no ST elevation was noted. All patients were seen by a neurologist and underwent neuropsychological testing. The patients were divided into two groups: those in need of a stent placement (group 1), those in need of coronary artery bypass grafting (group 2) and those with acute coronary syndrome ( group 3).Results: Assessment of cognitive functions with a Montreal cognitive assessment scale gave the following results: the total mean score in the group 1 was 24.3 ± 0.5, in the group 2, 26.3 ± 0.5 (normal at least 26), the difference between the groups being statistically significant (p = 0.0172). Cognitive impairment was more frequently found in acute coronary syndrome patients with ST elevation, who had more severe cardiac abnormalities, compared to those with acute coronary syndrome without ST elevation.Conclusion: Most patients with clinically significant atherosclerosis of coronary arteries have mild and moderate cognitive disorders, that indicate the importance of a neuropsychological screening for early detection of cognitive and neurological impairment in such patients.
Databáze: Directory of Open Access Journals
Externí odkaz: