A rare case of naturally occurring allo anti-Jk(a) missed in manual screening test on tube method

Autor: Ashish N Kanani, Snehal B Senjaliya, Manisha M Rajapara, Anurag K Gupta, Sanmukh R Joshi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Asian Journal of Transfusion Science, Vol 14, Iss 1, Pp 60-62 (2020)
Druh dokumentu: article
ISSN: 0973-6247
1998-3565
DOI: 10.4103/ajts.AJTS_104_19
Popis: Background: Antibodies to the Kidd blood group are mainly red blood cell (RBC) immune, but a few reports on naturally occurring antibodies have been documented. Aim: The aim of this study is to study the anti-Jk(a) for its unusual reactivity with different serological methods. Materials and Methods: Donor's plasma was tested with RBCs from in house donors and commercial panels by manual and automated devices. Results: A 36-year-old male blood donor with naturally occurring anti-Jk(a) is detected by solid-phase assays and the gel card technique but not by the tube method. The IgG antibody with the titer of >32 was not a complement-fixing hemolysin, showed a reduced reactivity with enzyme-treated RBCs, and was detectable through 8 months' follow-up period. The donor was typed as (Jk(a−). Conclusion: An unusual naturally occurring anti-Jk(a) detected by solid-phase red-cell adherence but not reacting by tube technique reflected on the sensitivity of the methods used.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje