The feasibility of colorectal endoscopic submucosal dissection for the treatment of residual or recurrent tumor localized in therapeutic scar tissue

Autor: Ryosuke Kobayashi, Kingo Hirasawa, Ryosuke Ikeda, Takeh de Fukuchi, Yasuaki Ishii, Hiroaki Kaneko, Makomo Makazu, Chiko Sato, Shin Maeda
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Endoscopy International Open, Vol 05, Iss 12, Pp E1242-E1250 (2017)
Druh dokumentu: article
ISSN: 2364-3722
2196-9736
DOI: 10.1055/s-0043-118003
Popis: Background and study aims Endoscopic submucosal dissection (ESD) is used to treat superficial colorectal tumors. Previous studies have reported the efficacy of ESD for treating residual or local recurrent colorectal tumors. This study sought to evaluate the efficacy of ESD in treating these lesions and to assess factors that prevent successful ESD. Methods This retrospective study assessed 25 cases of residual or local recurrent lesions that were previously treated using EMR (18 lesions), TEM (5 lesions), ESD (1 lesion) or surgery (1 lesion), and 459 primary lesions treated using ESD between April 2008 and September 2015. Clinicopathological characteristics, treatment outcome and adverse events were compared between groups with or without scar tissue. Factors related to perforation and a prolonged treatment time, which indicate the likelihood of technical difficulties, were identified using multiple logistic regression analysis. Results In residual or local recurrent lesions groups, patients experienced more perforations (32 % vs 4 %, P
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