Identification of osteogenic progenitor cell-targeted peptides that augment bone formation

Autor: Min Jiang, Ruiwu Liu, Lixian Liu, Alexander Kot, Xueping Liu, Wenwu Xiao, Junjing Jia, Yuanpei Li, Kit S. Lam, Wei Yao
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-17417-9
Popis: Activation of osteogenic cells is essential for bone regeneration. Here, the authors screen a peptide library and identify 2 compounds that promote osteogenic progenitor cell differentiation in vitro, and show that they increase bone formation and fracture repair in mice.
Databáze: Directory of Open Access Journals