| Autor: |
Timothy D Henry, Dean J Kereiakes, Joao A C Lima, Bharath Ambale-Venkatesh, Mohammad R Ostovaneh, Deborah Ascheim, Raj R Makkar, Tarun Chakravarty, Glen Kowalchuk, Frank V Aguirre, Thomas J Povsic, Richard Schatz, Jay H Traverse, Janice Pogoda, Rachel D Smith, Linda Marbán, Eduardo Marbán |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Open Heart, Vol 8, Iss 2 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2053-3624 |
| DOI: |
10.1136/openhrt-2021-001614 |
| Popis: |
Background Most cell therapy trials failed to show an improvement in global left ventricular (LV) function measures after myocardial infarction (MI). Myocardial segments are heterogeneously impacted by MI. Global LV function indices are not able to detect the small treatment effects on segmental myocardial function which may have prognostic implications for cardiac events. We aimed to test the efficacy of allogeneic cardiosphere-derived cells (CDCs) for improving regional myocardial function and contractility.Methods In this exploratory analysis of a randomised clinical trial, 142 patients with post-MI with LVEF |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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