Hypovitaminosis D as a risk factor for severe autism spectrum disorder

Autor: Diyah Rakanita Undang, Mei Neni Sitaresmi, Roni Naning
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Paediatrica Indonesiana, Vol 61, Iss 2, Pp 82-8 (2021)
Druh dokumentu: article
ISSN: 0030-9311
2338-476X
DOI: 10.14238/pi61.2.2021.82-8
Popis: Background Vitamin D is an important risk factor for autism spectrum disorder (ASD). However, research on hypovitaminosis D as a risk factor for severe ASD has been limited. To our knowledge, no such studies have been done in Indonesia. Objective To evaluate hypovitaminosis D as a risk factor for severe ASD. Methods This cross-sectional study included children aged 2-18 years who fulfilled the ASD DSM-5 diagnostic criteria. Subjects were consecutively sampled from April - June 2019 at the Child Growth and Polyclinic, Dr. Sardjito General Hospital, Yogyakarta. Assessment of ASD severity was carried out using the Childhood Autism Rating Scale Second Edition (CARS-2) questionnaire. Serum 25(OH)D examination was done in the Clinical Laboratory, Dr. Sardjito General Hospital. Results Of 36 children with ASD, 36.1% had hypovitaminosis D (
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