| Autor: |
Surendra Kumar Verma, Hessameddin Yaghoobi, Laurent Kreplak, John P. Frampton |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Advanced Materials Interfaces, Vol 10, Iss 4, Pp n/a-n/a (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2196-7350 |
| DOI: |
10.1002/admi.202202119 |
| Popis: |
Abstract Textiles containing interposed layers of polyethylene oxide (PEO)‐fibrinogen and PEO‐thrombin fibers are explored as biomaterials for hemostasis. The PEO‐fibrinogen and PEO‐thrombin fibers are formed by contact drawing, an approach that uses an entangled polymer solution and a pin array to form fibers by extension of liquid bridges. The interposition of the PEO‐fibrinogen and PEO‐thrombin fibers results in polymerization of a fibrin hydrogel mesh once the textile is hydrated. This fibrin hydrogel mesh displays the expected bands and diffraction peaks by Fourier‐transform infrared spectromicroscopy and X‐ray diffraction, respectively. The functionality of the hemostatic textiles formed from the interposed PEO‐fibrinogen and PEO‐thrombin fibers is demonstrated by analyzing human blood hemolysis, complement activation, protein adsorption, and platelet and leukocyte adhesion, indicating compatibility with human blood (hemolysis ratio |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Plný text