Identification of Long Non-Coding RNAs and Their Target Genes from Mycelium and Primordium in Model Mushroom Schizophyllum commune

Autor: Tuheng Wu, Jian Chen, Chunwei Jiao, Huiping Hu, Qingping Wu, Yizhen Xie
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Mycobiology, Vol 50, Iss 5, Pp 357-365 (2022)
Druh dokumentu: article
ISSN: 12298093
2092-9323
1229-8093
DOI: 10.1080/12298093.2022.2116819
Popis: AbstractSchizophyllum commune has emerged as the most promising model mushroom to study developmental stages (mycelium, primordium), which are two primary processes of fruit body development. Long non-coding RNA (lncRNA) has been proved to participate in fruit development and sex differentiation in fungi. However, potential lncRNAs have not been identified in S. commune from mycelium to primordium developmental stages. In this study, lncRNA-seq was performed in S. commune and 61.56 Gb clean data were generated from mycelium and primordium developmental stages. Furthermore, 191 lncRNAs had been obtained and a total of 49 lncRNAs were classified as differently expressed lncRNAs. Additionally, 26 up-regulated differently expressed lncRNAs and 23 down-regulated between mycelium and primordia libraries were detected. Further, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that differentially expressed lncRNAs target genes from the MAPK pathway, phosphatidylinositol signal, ubiquitin-mediated proteolysis, autophagy, and cell cycle. This study provides a new resource for further research on the relationship between lncRNA and two developmental stages (mycelium, primordium) in S. commune.
Databáze: Directory of Open Access Journals
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