Occult hepatitis B virus infection among injecting drug users in the Central-West Region of Brazil
| Autor: | Márcia Alves Dias de Matos, Renata Carneiro Ferreira, Fabiana Perez Rodrigues, Tamíris Augusto Marinho, Carmen Luci Rodrigues Lopes, Antônia Carlos Magalhães Novais, Ana Rita Coimbra Motta-Castro, Sheila Araújo Teles, Francisco José Dutra Souto, Regina Maria Bringel Martins |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 3, Pp 386-389 (2013) |
| Druh dokumentu: | article |
| ISSN: | 0074-0276 1678-8060 |
| Popis: | The prevalence of occult hepatitis B virus (HBV) infection was investigated in 149 hepatitis B surface antigen (HBsAg) negative injecting drug users (IDUs) in the Central-West Region of Brazil. Of these individuals, 19 were positive for HBV DNA, resulting in an occult HBV infection prevalence of 12.7% (19/149); six of these 19 individuals had anti-HBV core and/or anti-HBV surface antibodies and 13 were negative for HBV markers. All IDUs with occult hepatitis B reported sexual and/or parenteral risk behaviours. All HBV DNA-positive samples were successfully genotyped. Genotype D was the most common (17/19), followed by genotype A (2/19). These findings reveal a high prevalence of occult HBV infection and the predominance of genotype D among IDUs in Brazil's Central-West Region. |
| Databáze: | Directory of Open Access Journals |
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