| Autor: |
Kukulin Vladimir I., Bibikov Anton V., Tkalya Eugene V., Ceccarelli Matteo, Bodrenko Igor V. |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Biomolecular Concepts, Vol 14, Iss 1, Pp 193-9 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1868-503X |
| DOI: |
10.1515/bmc-2022-0028 |
| Popis: |
10B isotopes have been almost exclusively used in the neutron-capture radiation therapy (NCT) of cancer for decades. We have identified two other nuclides suitable for radiotherapy, which have ca. ten times larger cross section of absorption for neutrons and emit heavy charged particles. This would provide several key advantages for potential NCT, such as the possibility to use a lower nuclide concentration in the target tissues or a lower neutron irradiation flux. By detecting the characteristic γ radiation from the spontaneous decay of the radionuclides, one can image their biodistribution. These advantages could open up new possibilities for NCT applications as a safer and more efficient cancer therapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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