| Autor: |
Michael D. Tarpey, Kevin P. Davy, Ryan P. McMillan, Suzanne M. Bowser, Tanya M. Halliday, Nabil E. Boutagy, Brenda M. Davy, Madlyn I. Frisard, Matthew W. Hulver |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Molecular Metabolism, Vol 6, Iss 12, Pp 1597-1609 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2212-8778 |
| DOI: |
10.1016/j.molmet.2017.10.006 |
| Popis: |
Objective: We tested the hypothesis that skeletal muscle of endurance-trained male runners would exhibit elevated autophagy and mitophagy markers, which would be associated with greater metabolic flexibility following a high-fat meal (HFM). Methods: Muscle biopsies were collected to determine differences in autophagy and mitophagy protein markers and metabolic flexibility under fasting conditions and 4 h following a HFM between endurance-trained male runners (n = 10) and sedentary, non-obese controls (n = 9). Results: Maximal oxygen consumption (ml·kg·min−1) was approximately 50% higher (p 0.05), but increased in response to the HFM in endurance-trained athletes only (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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