Diagnosis of Evan´s syndrome

Autor: Andreas Angelopoulos, George Kirkilesis, Kiriaki Kakavia, Paraskevi Papanikolaou
Jazyk: English<br />French
Rok vydání: 2021
Předmět:
Zdroj: The Pan African Medical Journal, Vol 38, Iss 314 (2021)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2021.38.314.22410
Popis: This manuscript concerns the case of a patient hospitalized and diagnosed with Evans syndrome. She was hospitalized with signs of thrombocytopenia induced purpura, petechiae, ecchymosis and anemia. She was successfully treated with corticoids and blood transfusions. Our purpose is to explain her clinical presentation and the exams, we used in order to make the diagnosis of Evans syndrome, which requires great suspicion. Moreover, other diseases causing hemolytic anemia and thrombocytopenia must be excluded. We used laboratory tests (blood samples, Coombs examination and virologic test). Marrow examination took place twice. Evans syndrome is an autoimmune disease which is characterized by the coexistence of hemolytic anemia and immune-mediated thrombocytopenia. There is no typical clinical presentation. It´s etiology is unknown and its therapy is generally poor. Diagnosis of Evans syndrome is very difficult and requires the exclusion of other diseases causing anemia and thrombocytopenia.
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