Granulomatosis with Polyangiitis: Recurrence or Treatment Consequences?

Autor: Andreia Diegues, Joana Tavares, Diogo Sá, João Oliveira, Diana Fernandes, Josefina Santos, Guillerme Rocha
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2021)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2021_002448
Popis: Granulomatosis with polyangiitis (GPA) is the most common antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We describe the case of a 38-year-old woman with relapsing GPA who presented with intracranial hypertension, followed by the appearance of cavitated lung nodules despite treatment with azathioprine. Clinical improvement and ANCA titre reduction were observed after rituximab treatment. We report a rare form of GPA relapse and highlight the challenge of following-up patients with GPA, in whom can be hard to distinguish relapse from the consequences of long-term immunosuppression.
Databáze: Directory of Open Access Journals