Serological follow up of positive SARS-CoV-2 cases

Autor: José Gerardo González-González, Adrián Camacho-Ortiz, René Rodríguez-Gutiérrez, Donato Saldívar-Rodríguez, Luz Adriana Ramírez-García, Adriana Sánchez-García
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2022
Předmět:
Zdroj: Salud Pública de México, Vol 64, Iss 3, may-jun, Pp 243-248 (2022)
Druh dokumentu: article
ISSN: 0036-3634
DOI: 10.21149/13065
Popis: Objective. To describe the humoral response in a cohort with mild and asymptomatic SARS-CoV-2 infection previ­ously identified in a community-based serological survey. Materials and methods. This study was an observational follow up of 193 subjects previously identified with positive anti-SARS-CoV-2 antibodies invited for a second test 112 days after the first sampling. All completed a standardized electronic questionnaire. IgM/IgG antibodies were determined using a qualitative IgM/IgG chemiluminescent immunoassay. Results. Among the 193 eligible subjects, a total of 174 (90%) attended the follow-up visit, and their serum samples were tested. Of the samples, 171 (98.3%) were still positive, and 3 (1.7%) were negative. Also, the cut-off index (COI) value of the immunoassay significantly increased from the first to the second test (P
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