Diffusely distributed centrilobular micronodules and branching opacities as the main chest computed tomography manifestations in a patient with humidifier lung

Autor: Chinatsu Nakane, Takahiro Teshima, Ryosuke Otake, Emiko Nakagawa, Ei Kishimoto, Kosuke Suzuki, Ryunosuke Inaba, Yurina Murakami, Yoichiro Aoshima, Koji Nishimoto, Sayomi Matsushima, Masanori Harada, Shiro Imokawa
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 51, Iss , Pp 102061- (2024)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2024.102061
Popis: We report a 60-year-old man with humidifier lung showing diffusely distributed centrilobular micronodules and branching opacities on chest computed tomography (CT). Fever and dyspnea occurred 2 months after using an ultrasonic humidifier. KL-6 and SP-D were within normal ranges. Bronchoalveolar lavage showed elevated lymphocytes (53 %) and histological findings of transbronchial lung biopsy demonstrated organizing pneumonia. His condition improved after cessation of the humidifier. A provocation test exhibited a positive response to the humidifier. Humidifier lung should be considered as a differential diagnosis in patients with these CT findings. Detailed clinical, pathological and microbiological examinations are needed to exclude other diseases.
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