COVID‐19 infection in patients with connective tissue disease: A multicity study in Hubei province, China

Autor: Cong Ye, Jixin Zhong, Shaozhe Cai, Li Dong, Chuanjing Li, Xiaoqiang Hou, Xiaoqi Chen, Anbing Zhang, Wenli Chen, Dongchu He, Tao Zhou, Guilian Shang, Aichun Chu, Huiling Li, Qihuan Liu, Bin Wu, Xiangdong Yu, Tao Peng, Cheng Wen, Gang Hong Huang, Hao Huang, Qin Huang, Linchong Su, Wenping Chen, Huiqin Yang, Lingli Dong
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: MedComm, Vol 2, Iss 1, Pp 82-90 (2021)
Druh dokumentu: article
ISSN: 2688-2663
DOI: 10.1002/mco2.56
Popis: Abstract Novel Coronavirus disease 2019 (COVID‐19) has spread rapidly around the world. Individuals with immune dysregulation and/or on immunosuppressive therapy, such as rheumatic patients, are considered at greater risk for infections. However, the risks of patients with each subcategory of rheumatic diseases have not been reported. Here, we identified 100 rheumatic patients from 18,786 COVID‐19 patients hospitalized in 23 centers affiliated to Hubei COVID‐19 Rheumatology Alliance between January 1 and April 1, 2020. Demographic information, medical history, length of hospital stay, classification of disease severity, symptoms and signs, laboratory tests, disease outcome, computed tomography, and treatments information were collected. Compared to gout and ankylosing spondylitis (AS) patients, patients with connective tissue disease (CTD) tend to be more severe after COVID‐19 infection (p = 0.081). CTD patients also had lower lymphocyte counts, hemoglobin, and platelet counts (p values were 0.033,
Databáze: Directory of Open Access Journals