Parkinson’s Disease Is Associated With Dysregulation of Circulatory Levels of lncRNAs

Autor: Kasra Honarmand Tamizkar, Pooneh Gorji, Mahdi Gholipour, Bashdar Mahmud Hussen, Mehrdokht Mazdeh, Solat Eslami, Mohammad Taheri, Soudeh Ghafouri-Fard
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Immunology, Vol 12 (2021)
Druh dokumentu: article
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.763323
Popis: Long non-coding RNAs (lncRNAs) have been recently reported to be involved in the pathoetiology of Parkinson’s disease (PD). Circulatory levels of lncRNAs might be used as markers for PD. In the present work, we measured expression levels of HULC, PVT1, MEG3, SPRY4-IT1, LINC-ROR and DSCAM-AS1 lncRNAs in the circulation of patients with PD versus healthy controls. Expression of HULC was lower in total patients compared with total controls (Expression ratio (ER)=0.19, adjusted P value
Databáze: Directory of Open Access Journals