Development of Antibacterial Resin Composites Incorporating Poly(METAC) Clusters

Autor: Tomoki Kohno, Haruaki Kitagawa, Ririko Tsuboi, Fan Deng, Hirohiko Sakai, Tingyi Wu, Yo-Shiuan Fan, Linghao Xiao, Satoshi Imazato
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Materials, Vol 17, Iss 4, p 896 (2024)
Druh dokumentu: article
ISSN: 1996-1944
DOI: 10.3390/ma17040896
Popis: This study examined the antibacterial effects and physical properties of a novel resin composite incorporating poly[{2-(methacryloyloxy)ethyl}trimethylammonium chloride] (poly(METAC)), a methacrylate cationic polymer comprising quaternary ammonium compounds (QACs). Resin composites incorporating poly(METAC) were fabricated by adding 6 wt.% METAC aqueous solution to a commercially available resin composite. The FE-SEM/EDS and Raman spec-troscopy analyses showed that METAC was assembled and polymerized in the resin composites after curing. The antibacterial effect was evaluated by inoculating Streptococcus mutans or Strepto-coccus sobrinus suspensions on the surface of cured resin composites, and the experimental resin composites incorporating poly(METAC) clusters exhibited bactericidal effects even after 28 days of ageing. The physical properties of the experimental resin composites were within the ISO-stipulated ranges. Newly fabricated resin composites containing the QAC-based poly(METAC) cluster ex-hibited long-term bactericidal effects against oral bacteria on their surfaces and demonstrated ac-ceptable physical properties for clinical use.
Databáze: Directory of Open Access Journals
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