Hepatobiliary neuroendocrine carcinoma: a case report

Autor: Loxha Sadushe, Sahatciu-Meka Vjollca, Maloku Halit, Petrusevska Gordana, Manxhuka-Kerliu Suzana, Loxha Naim, Shahini Labinot
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 4, Iss 1, p 53 (2010)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/1752-1947-4-53
Popis: Abstract Introduction Neuroendocrine carcinoma of the gallbladder is a rather uncommon disease. We report a case of a neuroendocrine tumor that was located in the wall of the gallbladder and that extended into the liver. Case presentation A 52-year-old Caucasian woman presented with right-sided abdominal pain, ascites and jaundice. An MRI scan revealed a tumor mass located in the gallbladder wall and involving the liver. A partial hepatectomy and cholecystectomy were performed. Histology revealed a neuroendocrine tumor, which showed scattered Grimelius positive cells and immuno-expressed epithelial and endocrine markers. Our patient is undergoing chemotherapy treatment. Conclusion Gastroenteropancreatic neuroendocrine tumors need a multidisciplinary approach, involving immunohistochemistry and molecular-genetic techniques.
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