Current pathogens infecting open fracture tibia and their antibiotic susceptibility at a tertiary care teaching hospital in South East Asia

Autor: Md. Samiul Islam, Syed Shahidul Islam, Sultana Parvin, Mushfique Manjur, Muhammad Rafiqul Islam, Rabin Chandra Halder, Mohd. Sayedul Islam, Syed Khaledur Rahaman, Mobinul Hoque, Md. Omar Faruque, A.K.M. Nazmul Haque
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Infection Prevention in Practice, Vol 4, Iss 1, Pp 100205- (2022)
Druh dokumentu: article
ISSN: 2590-0889
DOI: 10.1016/j.infpip.2022.100205
Popis: Summary: Background: Tibia fractures represent the most prevalent open long-bone injuries. Indiscriminate, extensive, and unnecessary use of antibiotics has led to the emergence of infections caused by multidrug resistant organisms that increase morbidity and mortality. This study evaluated the spectrum of current organisms infecting the open tibia fractures and their antibiotic susceptibility pattern. This research did not alter the exiting practice of the institute to evaluate the current status. Methods: This was a cross-sectional study on 628 patients presenting with open fractures of the tibia from July 2018 to July 2020. Sampling for three successive culture (and sensitivity) tests were carried out, 1st on specimens taken in the emergency room (upon patient presentation), 2nd in the emergency theatre after initial debridement, and 3rd in the ward between 12 to 14 days post operatively. Results: The average age of the patients was 36.2± 15.4 years, with motor vehicle accidents being the predominant aetiology (72.2%). Results of specimen culture demonstrated that debridement could reduce microbial contamination significantly (P
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