Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice

Autor: Dalong Ni, Dawei Jiang, Christopher J. Kutyreff, Jianhao Lai, Yongjun Yan, Todd E. Barnhart, Bo Yu, Hyung-Jun Im, Lei Kang, Steve Y. Cho, Zhaofei Liu, Peng Huang, Jonathan W. Engle, Weibo Cai
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-07890-8
Popis: There are currently no effective therapies available for acute kidney injury (AKI). Here the authors generate molybdenum-based polyoxometalate nanoclusters and show that these have preferential renal uptake and can ameliorate AKI pathology in mice by scavenging reactive oxygen species.
Databáze: Directory of Open Access Journals