Prevalence of thoracic aortic aneurysm in patients referred for no/low-charge coronary artery calcium scoring: Insights from the CLARIFY registry

Autor: Tasveer Khawaja, Scott E Janus, Nour Tashtish, Matthew Janko, Cristian Baeza, Robert Gilkeson, Sadeer G. Al-Kindi, Sanjay Rajagopalan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: American Journal of Preventive Cardiology, Vol 12, Iss , Pp 100378- (2022)
Druh dokumentu: article
ISSN: 2666-6677
DOI: 10.1016/j.ajpc.2022.100378
Popis: Objective: Low-dose cardiac-gated chest CTs allow for simultaneous evaluation of coronary artery calcification and aortic size. We sought to evaluate the prevalence of thoracic aortic dilation (TAD) and thoracic aortic aneurysm (TAA) in a large cohort of patients undergoing coronary artery calcium (CAC) screening. Methods: We reviewed all patients from a large, prospective no-charge CAC screening program (CLARIFY, Clinicaltrials.gov NCT04075162) for whom measurements of the ascending aorta were available. TAD was defined as an ascending aortic diameter ≥4.0cm, while TAA was defined as ascending aortic diameter ≥ 4.5cm. We explored associations between patient characteristics, CAC, and the prevalence of TAD/TAA. Results: A total of 36,356 patients enrolled in the CLARIFY program underwent analysis for TAD/TAA. 3,130 patients (8.6%) had TAD and 237 (0.7%) had TAA. Patients with TAA were older (63±8 vs 59±10 years, p
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