Systemic amyloid A amyloidosis of the bladder after transurethral resection of urothelial carcinoma

Autor: Kaori Yamashita, Keita Yoshida, Tadao Nakazawa, Satoshi Kubota, Takahiro Shiseki, Eri Sekido, Masashi Inui
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: IJU Case Reports, Vol 7, Iss 3, Pp 274-276 (2024)
Druh dokumentu: article
ISSN: 2577-171X
DOI: 10.1002/iju5.12715
Popis: Introduction Amyloid A amyloidosis of the bladder is not a major disease. We report a patient with systemic amyloid A amyloidosis of the bladder after transurethral resection of urothelial carcinoma. Case presentation An 87‐year‐old Japanese man had bladder carcinoma. He was followed up regularly with cystoscopy. Cystoscopy revealed multiple polypoid tumors 6 months after the first transurethral resection of urothelial carcinoma. Pathologic specimens contained the amyloid A component. He had hypertrophic cardiomyopathy, valvular disorders, and arrhythmias. His cardiac disease may have resulted from amyloid A amyloidosis. We speculated the patient had systemic amyloid A amyloidosis of the heart and bladder. Conclusion We determined the type of amyloidosis via a biopsy of the bladder tumors. Our patient had cardiac disease. Therefore, systemic amyloid A amyloidosis could have caused his cardiac disease. The pathologic findings of bladder tumors can contribute to detecting systemic amyloid A amyloidosis.
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