Sex differences in myocardial injury after non-cardiac surgery and postoperative mortality

Autor: Ji-Hye Kwon, Jungchan Park, Seung-Hwa Lee, Cheol Won Hyun, Jihoon Kim, Kwangmo Yang, Jeong Jin Min, Jong Hwan Lee, Sangmin Maria Lee, Jin-ho Choi, Sang-Chol Lee, Hyeon-Cheol Gwon, Sukyoung Her, Kyunga Kim, Joonghyun Ahn
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Perioperative Medicine, Vol 12, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 2047-0525
DOI: 10.1186/s13741-023-00294-3
Popis: Abstract Background Myocardial injury after non-cardiac surgery (MINS) has recently been accepted as a predictor of mortality. However, sex differences in the incidence of MINS and survival thereafter are not fully understood. This study aimed to compare the incidence of MINS and mortality among male and female patients. Methods This single-center study was conducted using the database of a large tertiary referral hospital. Consecutive patients with cardiac troponin (cTn) detected within 30 days after non-cardiac surgery performed between January 2010 and June 2019 were grouped according to sex. The incidence of MINS and mortality of patients with MINS were compared between men and women. Results Of the 33,311 patients, 18,546 (55.7%) were men and 14,765 (44.3%) were women. In a multivariable analysis, women showed a significantly lower incidence of MINS than did men (17.9% vs. 14.2%; odds ratio, 0.76; 95% confidence interval [CI], 0.71–0.81; P
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