Autor: |
Nilay Sutaria, Ching-Ti Liu, Tai C. Chen |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
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Zdroj: |
Journal of Clinical & Translational Endocrinology, Vol 1, Iss 4, Pp 151-160 (2014) |
Druh dokumentu: |
article |
ISSN: |
2214-6237 |
DOI: |
10.1016/j.jcte.2014.08.001 |
Popis: |
Objective: To investigate the impacts of vitamin D status, supplementation and vitamin D receptor (VDR) gene polymorphisms on tuberculosis (TB). Methods: We conducted a systematic review of published studies pertaining to case–control and randomized-control trials from 2002 to 2014 using the PubMed database. Results and conclusion: Individuals with TB have lower vitamin D status than healthy individuals. Some VDR gene polymorphisms are associated with increased susceptibility to TB while others may not. Supplementation with vitamin D leads to improved clinical outcomes. However, further studies with a larger patient population and different ethnicities are needed to confirm these effects. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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