Single- and multiple-dose pharmacokinetics of ethambutol and rifampicin in a tuberculosis patient with acute respiratory distress syndrome undergoing extended daily dialysis and ECMO treatment

Autor: Ann-Kathrin Strunk, Sandra Ciesek, Julius J. Schmidt, Christian Kühn, Marius M. Hoeper, Tobias Welte, Jan T. Kielstein
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 42, Iss C, Pp 1-3 (2016)
Druh dokumentu: article
ISSN: 1201-9712
1878-3511
DOI: 10.1016/j.ijid.2015.10.018
Popis: The dosing of drugs in critically ill patients undergoing renal replacement therapy is based on limited data. We report for the first time single- and multiple-dose pharmacokinetics of ethambutol (EMB), which is cleared renally to 80%, and rifampicin (RIF), which is cleared renally to
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